Junfeng Liang (jliang2)

Junfeng Liang

Professor

Charles V. Schaefer, Jr. School of Engineering and Science

Department of Chemistry and Chemical Biology

McLean Hall 513
(201) 216-5640
(201) 216-8196
Website

Research

Laboratory of Pharmaceutical Chemistry and Engineering
Research Areas:
1. Therapeutic Peptides: We are interested in a new peptide design and delivery technology aimed at developing new therapeutic peptides for a wide array of pharmaceutical applications.
2. Bacteria Responsive Materials for Medical Device Infections and Bio-Fouling. We are working on polymeric antibacterial coatings designed specifically for implants associated infections through inducing autolysis which kills bacteria.
3. Nano-Technology Enabled Cell Sensing and Drug Delivery. Nano-technology is used in cell sensing in combination with peptides and signaling messengers. In addition, novel nano-formulation technologies are also studied for improved drug therapeutic effectiveness and repurposing.

Experience

Professor and Associate Professor, Department of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, 2003-present
Assistant Research Professor, Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, 2000-2002
Associate Professor and Lecturer, School of Life Sciences, Tsinghua University, Beijing, 1993-1999

Institutional Service

  • Institutional Biosafety Committee Member
  • P&T committee of CCB Member
  • P&T committee of CCB Member
  • P&T committee of SES Member
  • P&T committee of CCB Member
  • P&T committee of SES Member
  • SES Shared Biomedical Research Facility Member
  • faculty search committee Member
  • Lecture search committee Member
  • Bioengineering Program director Chair
  • Engineering School P&T committee Member
  • P&T committee of CCB Chair
  • Graduate Student recuritiing committee Member
  • Engineering School P&T committee Member

Professional Societies

  • AAPS – American Association of Pharmaceutical Scientists Member
  • ACS – American Chemical Society Member
  • Institution of Engineering and Technology Fellow
  • AAPS – American Association of Pharmaceutical Scientists Member
  • ACS – American Chemical Society Member
  • Institution of Engineering and Technology Fellow
  • AAPS – American Association of Pharmaceutical Scientists Member
  • ACS – American Chemical Society Member
  • Institution of Engineering and Technology Fellow
  • AAPS – American Association of Pharmaceutical Scientists Member
  • ACS – American Chemical Society Member
  • Institution of Engineering and Technology Fellow

Selected Publications

Data Paper, Journal

  1. Chang, T. L.; Liu, T.; Liang, J. F. (2018). The dataset of scanning electron microscope images of silver nanoparticles formed in situ by dopamine chemistry. Data in Brief (vol. 20, pp. 1090-1092).

Journal Article

  1. Ruppel, S. S.; Li, R.; Liang, J. (2023). Glucose controlled surface coating with polydopamine. Colloids and Surfaces A: Physicochemical and Engineering Aspects (vol. 673).
  2. He, S.; Wang, J.; Yang, F.; Chang, T. L.; Tang, Z.; Liu, K.; Liu, S.; Tian, F.; Liang, J. F.; Du, H.; Liu, Y. (2023). Bacterial Detection and Differentiation of Staphylococcus aureus and Escherichia coli Utilizing Long-Period Fiber Gratings Functionalized with Nanoporous Coated Structures. Coatings (4 ed., vol. 13).
  3. Chen, S.; Liang, J. F. (2023). Anticancer Activity of Nano-formulated Orlistat-Dopamine Conjugates Through Self-Assembly. Bioconjugate Chemistry (3 ed., vol. 34, pp. 581-593).
  4. Liu, T.; Chang, T. L.; Zhou, X.; Ruppel, S.; Liang, J. F. (2023). Phase separation enabled silver nano-array. Nanotechnology (6 ed., vol. 34).
  5. Ruppel, S. S.; Liang, J. (2023). Surface mineralization with controlled polymerization of dopamine. Journal of Applied Polymer Science.
  6. Su, T.; Chen, T.; Liang, J. (2022). Green in-situ synthesis of silver coated textiles for wide hygiene and healthcare applications. Colloids and Surfaces A: physicochemical and Engineering Aspects (657 (2023) 130506 ed.).
  7. Ruppel, S. S.; Liang, J. (2022). Tunable Properties of Polydopamine Nanoparticles and Coated Surfaces. Langmuir (16 ed., vol. 38, pp. 5020-5029).
  8. Ruppel, S. S.; Liang, J. (2022). Tunable Properties of Polydopamine Nanoparticles and Coated Surfaces. Langmuir (16 ed., vol. 38, pp. 5020-5029).
  9. Chang, T. L.; Sun, P. K.; Zhou, X.; Besser, R.; Liang, J. (2020). Preparation and electrochemical performances of silver (alloy) nanoparticles decorated on reduced graphene oxide, using self-polymerization of dopamine in an acidic environment. Materials Today Chemistry (vol. 17).
  10. Chang, T. L.; Sun, P. K.; Zhou, X.; Besser, R.; Liang, J. (2020). Preparation and electrochemical performances of silver (alloy) nanoparticles decorated on reduced graphene oxide, using self-polymerization of dopamine in an acidic environment. Materials Today Chemistry (vol. 17).
  11. Chang, T. L.; Sun, P. K.; Zhou, X.; Besser, R.; Liang, J. (2020). Preparation and electrochemical performances of silver (alloy) nanoparticles decorated on reduced graphene oxide, using self-polymerization of dopamine in an acidic environment. Materials Today Chemistry (vol. 17).
  12. Zhou, X.; Hou, C.; Chang, T. L.; Zhang, Q.; Liang, J. F. (2020). Controlled released of drug from doubled-walled PVA hydrogel/PCL microspheres prepared by single needle electrospraying method. Colloids and Surfaces B: Biointerfaces (vol. 187).
  13. Zhou, X.; Hou, C.; Chang, T. L.; Zhang, Q.; Liang, J. (2020). Controlled released of drug from doubled-walled PVA hydrogel/PCL microspheres prepared by single needle electrospraying method.. Colloids and surfaces. B, Biointerfaces (vol. 187, pp. 110645).
  14. Xu, J.; Zhao, H.; Xie, Z.; Ruppel, S.; Zhou, X.; Chen, S.; Liang, J. F.; Wang, X. (2019). Stereochemical Strategy Advances Microbially Antiadhesive Cotton Textile in Safeguarding Skin Flora. Advanced Healthcare Materials (15 ed., vol. 8).
  15. Xu, J.; Zhao, H.; Xie, Z.; Ruppel, S.; Zhou, X.; Chen, S.; Liang, J. F.; Wang, X. (2019). Stereochemical Strategy Advances Microbially Antiadhesive Cotton Textile in Safeguarding Skin Flora. Advanced Healthcare Materials (15 ed., vol. 8).
  16. Zhou, X.; Chang, T. L.; Chen, S.; Liu, T.; Wang, H.; Liang, J. F. (2019). Polydopamine-Decorated Orlistat-Loaded Hollow Capsules with an Enhanced Cytotoxicity against Cancer Cell Lines. Molecular Pharmaceutics (6 ed., vol. 16, pp. 2511-2521).
  17. Zhou, X.; Chang, T. L.; Chen, S.; Liu, T.; Wang, H.; Liang, J. F. (2019). Polydopamine-Decorated Orlistat-Loaded Hollow Capsules with an Enhanced Cytotoxicity against Cancer Cell Lines. Molecular Pharmaceutics (6 ed., vol. 16, pp. 2511-2521).
  18. Zhou, X.; Chang, T. L.; Chen, S.; Liu, T.; Wang, H.; Liang, J. F. (2019). Polydopamine-Decorated Orlistat-Loaded Hollow Capsules with an Enhanced Cytotoxicity against Cancer Cell Lines. Molecular Pharmaceutics (6 ed., vol. 16, pp. 2511-2521).
  19. Yang, F.; Chang, T. L.; Liu, T.; Wu, D.; Du, H.; Liang, J.; Tian, F. (2019). Label-free detection of Staphylococcus aureus bacteria using long-period fiber gratings with functional polyelectrolyte coatings. Biosensors and Bioelectronics (vol. 133, pp. 147-153).
  20. Yang, F.; Chang, T. L.; Liu, T.; Wu, D.; Du, H.; Liang, J.; Tian, F. (2019). Label-free detection of Staphylococcus aureus bacteria using long-period fiber gratings with functional polyelectrolyte coatings. Biosensors and Bioelectronics (vol. 133, pp. 147-153).
  21. Yang, F.; Chang, T. L.; Liu, T.; Wu, D.; Du, H.; Liang, J.; Tian, F. (2019). Label-free detection of Staphylococcus aureus bacteria using long-period fiber gratings with functional polyelectrolyte coatings. Biosensors and Bioelectronics (vol. 133, pp. 147-153).
  22. Chang, T. L.; Zhou, X.; Liang, J. (2019). Synthesis and characterization of Ag-Cu alloy nanoparticles for antimicrobial applications: A polydopamine chemistry application. Materials Science and Engineering C (vol. 98, pp. 675-684).
  23. Chang, T. L.; Zhou, X.; Liang, J. (2019). Synthesis and characterization of Ag-Cu alloy nanoparticles for antimicrobial applications: A polydopamine chemistry application. Materials Science and Engineering C (vol. 98, pp. 675-684).
  24. Chang, T. L.; Zhou, X.; Liang, J. (2019). Synthesis and characterization of Ag-Cu alloy nanoparticles for antimicrobial applications: A polydopamine chemistry application. Materials Science and Engineering C (vol. 98, pp. 675-684).
  25. Liu, T.; Yang, F.; Wang, X.; Liang, J. F. (2019). Adhesive Gold Nanoparticles for Easy and Controlled Surface Coating. Langmuir (7 ed., vol. 35, pp. 2728-2737).
  26. Liu, T.; Yang, F.; Wang, X.; Liang, J. F. (2019). Adhesive Gold Nanoparticles for Easy and Controlled Surface Coating. Langmuir (7 ed., vol. 35, pp. 2728-2737).
  27. Liu, T.; Yang, F.; Wang, X.; Liang, J. F. (2019). Adhesive Gold Nanoparticles for Easy and Controlled Surface Coating. Langmuir (7 ed., vol. 35, pp. 2728-2737).
  28. Zhou, X.; Li, Y.; Chen, S.; Fu, Y. n.; Wang, S.; Li, G.; Tao, L.; Wei, Y.; Wang, X.; Liang, J. F. (2018). Dynamic agent of an injectable and self-healing drug-loaded hydrogel for embolization therapy. Colloids and Surfaces B: Biointerfaces (vol. 172, pp. 601-607).
  29. Liang, Y.; Xu, C.; Li, G.; Liu, T.; Liang, J. F.; Wang, X. (2018). Graphene-kaolin composite sponge for rapid and riskless hemostasis. Colloids and Surfaces B: Biointerfaces (vol. 169, pp. 168-175).
  30. Chen, T. P.; Liang, J.; Su, T. L. (2018). Plasma-activated water: antibacterial activity and artifacts?. Environmental Science and Pollution Research (27 ed., vol. 25, pp. 26699-26706).
  31. Chen, T. P.; Liang, J.; Su, T. (2018). Plasma-activated water: antibacterial activity and artifacts?. Environmental science and pollution research international (27 ed., vol. 25, pp. 26699-26706).
  32. Liu, T.; Liang, J. F. (2018). Nanostructured surfaces from high-density grafted poly (acrylic acid) with liquid-like property. Reactive and Functional Polymers (vol. 127, pp. 123-128).
  33. Chang, T. L.; Yu, X.; Liang, J. F. (2018). Polydopamine-enabled surface coating with nano-metals. Surface and Coatings Technology (vol. 337, pp. 389-395).
  34. Chen, T.; Su, T.; Liang, J. (2017). Plasma-activated solutions for bacteria and biofilm inactivation. Current Bioactive Compounds (1 ed., vol. 13, pp. 59--65). Bentham Science Publishers.
  35. Chen, T.; Liu, T.; Su, T.; Liang, J. (2017). Self-polymerization of dopamine in acidic environments without oxygen. Langmuir (23 ed., vol. 33, pp. 5863--5871). ACS Publications.
  36. Zhou, X.; Liang, J. F. (2017). A fluorescence spectroscopy approach for fast determination of β-cyclodextrin-guest binding constants. Journal of Photochemistry and Photobiology A: Chemistry (vol. 349, pp. 124-128).
  37. Sun, F.; Ding, X.; Xu, L.; Liang, J. F.; Chen, L.; Luo, S. Z. (2017). A Molecular Dynamics Study of the Short-Helical-Cytolytic Peptide Assembling and Bioactive on Membrane Interface. Journal of Physical Chemistry C (32 ed., vol. 121, pp. 17263-17275).
  38. Sun, F.; Chen, L.; Ding, X.; Xu, L.; Zhou, X.; Wei, P.; Liang, J. F.; Luo, S. Z. (2017). High-Resolution Insights into the Stepwise Self-Assembly of Nanofiber from Bioactive Peptides. Journal of Physical Chemistry B (31 ed., vol. 121, pp. 7421-7430).
  39. Voloshchuk, N.; Chen, L.; Li, Q.; Liang, J. F. (2017). Peptide oligomers from ultra-short peptides using sortase. Biochemistry and Biophysics Reports (vol. 10, pp. 1-6).
  40. Chen, T. P.; Liu, T.; Su, T. L.; Liang, J. (2017). Self-polymerization of dopamine in acidic environments without oxygen. Langmuir (23 ed., vol. 33, pp. 5863-5871).
  41. Zhan, H.; Jagtiani, T.; Liang, J. F. (2017). A new targeted delivery approach by functionalizing drug nanocrystals through polydopamine coating. European Journal of Pharmaceutics and Biopharmaceutics (vol. 114, pp. 221-229).
  42. Zhan, H.; Liang, J. F. (2017). Preparation and anticancer activity evaluation of an amorphous drug nanocomposite by simple heat treatment. Anti-Cancer Drugs (6 ed., vol. 28, pp. 623-633).
  43. Zhan, H.; Zhou, X.; Cao, Y.; Jagtiani, T.; Chang, T. L.; Liang, J. F. (2017). Anti-cancer activity of camptothecin nanocrystals decorated by silver nanoparticles. Journal of Materials Chemistry B (14 ed., vol. 5, pp. 2692-2701).
  44. Chen, T. P.; Su, T. L.; Liang, J. (2017). Plasma-activated solutions for bacteria and biofilm inactivation. Current Bioactive Compounds (1 ed., vol. 13, pp. 59-65).
  45. Zhan, H.; Liang, J. F. (2016). Extreme Activity of Drug Nanocrystals Coated with A Layer of Non-Covalent Polymers from Self-Assembled Boric Acid. Scientific Reports (vol. 6).
  46. Zhan, H.; Jagtiani, T.; Liang, J. F. (2016). Enhanced anticancer activity of drug nanoparticles formulated with β-cyclodextrin. Anti-Cancer Drugs (3 ed., vol. 28, pp. 271-280).
  47. Li, B.; Liang, J. F. (2016). A linker approach to phospholipopeptides. European Journal of Lipid Science and Technology (2 ed., vol. 118, pp. 273-278).
  48. Voloshchuk, N.; Liang, D.; Liang, J. F. (2015). Sortase a mediated protein modifications and peptide conjugations. Current Drug Discovery Technologies (4 ed., vol. 12, pp. 205-213).

Other

  1. Xi, Y.; Choi, C.; Yu, X.; Liang, J. (2020). Artificial Cornea with Double-Side Microtextured pHEMA Hydrogel.
  2. Chang, T. L.; Liu, T.; Liang, J. F. (2018). The dataset of scanning electron microscope images of silver nanoparticles formed in situ by dopamine chemistry. Data in Brief (vol. 20, pp. 1090-1092).